Department of Medical Toxicology

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Steven C. Curry, MD, FACMT, FACCT

Professor of Biomedical Informatics, Emergency Medicine, and Internal Medicine
Co-Director, Division of Clinical Data Analytics and Decision Support, Department of Internal Medicine, University of Arizona College of Medicine - Phoenix


Board Certifications Emergency Medicine
Medical Toxicology
Fellowship St. Luke's Hospital (Phoenix, AZ)
Residency Methodist Hospital (Indianapolis, IN)

Recent Publications

Peer-Reviewed Research Articles

  1. Akakpo JY, Ramachandran A, Orhan H, Curry SC, Rumack BH, Jaeschke H. 4-methylpyrazole protects against acetaminophen-induced acute kidney injury. Toxicol Appl Pharmacol. 2020 Nov 3:115317. doi: 10.1016/j.taap.2020.115317
  2. Heise CW, Gallo T, Curry SC, Woosley RL. (2020). Identification of populations likely to benefit from pharmacogenomic testing. Pharmacogenet Genomics. 2020 Mar 23. doi: 10.1097/FPC.0000000000000400. [Epub ahead of print]
  3. Kang AM, Padilla-Jones A, Fisher ES, Akakpo JY, Jaeschke H, Rumack BH, Gerkin RD, Curry SC. The Effect of 4-Methylpyrazole on Oxidative Metabolism of Acetaminophen in Human Volunteers. J Med Toxicol. 2019; in press. Doi: 10.1007/s13181-019-00740-z
  4. Curry SC, Padilla-Jones A, Ruha AM, O'Connor AD, Kang AM, Wilkins DG, Jaeschke H, Wilhelms K, Gerkin RD, Acetaminophen Adduct Study Group. The Relationship Between Circulating Acetaminophen-Protein Adduct Concentrations and Alanine Aminotransferase Activities in Patients With and Without Acetaminophen Overdose and Toxicity. J Med Toxicol. 2019 Apr 12. doi: 10.1007/s13181-019-00705-2. [Epub ahead of print]
  5. Gallo T, Curry SC, Padilla-Jones A, Heise CW, Ramos KS, Woosley RL, Raschke RA. A Computerized Scoring System to Improve Assessment of Heparin-induced Thrombocytopenia Risk. J Thromb Haemost. 2018 Dec 14. doi: 10.1111/jth.14359. [Epub ahead of print]
  6. Duan L, Ramachandran A, Akakpo JY, Weemhoff JL, Curry SC, Jaeschke H. Role of extracellular vesicles in release of protein adducts after acetaminophen-induced liver injury in mice and humans. Toxicol Lett. 2018 Nov 14. pii: S0378-4274(18)32002-2. doi: 10.1016/j.toxlet.2018.11.005.
  7. Raschke RA, Groves RH, Khurana HS, et al. A quality improvement project to improve the Medicare and Medicaid Services (CMS) sepsis bundle compliance rate in a large healthcare system. BMJ Open Qual. 2017 Oct 21;6(2):e000080. doi: 10.1136/bmjoq-2017-000080
  8. Raschke RA, Gallo T, Curry SC, et al. Clinical effectiveness of a Bayesian algorithm for the diagnosis and management of heparin-induced thrombocytopenia. J Thromb Haemost. 2017 Jun 16. doi: 10.1111/jth.13758
  9. Weemhoff JL, Woolbright BL, Jenkins RE, et al. Plasma biomarkers to study mechanisms of liver injury in patients with hypoxic hepatitis. Liver Int. 2017;37:377-384. doi:10.1111/liv.13202.
  10. Lasoff DR, Ruha AM, Curry SC, et al. A new F(ab')(2) antivenom for the treatment of crotaline envenomation in children. Am J Emerg Med. 2016 Oct;34(10):2003-2006. doi: 10.1016/j.ajem.2016.07.061.
  11. Thomas KC, Wilkins DG, Curry SC, et al. Detection of Acetaminophen-Protein Adducts in Decedents with Suspected Opioid-Acetaminophen Combination Product Overdose. J Forensic Sci. 2016 Sep;61(5):1301-6. doi: 10.1111/1556-4029.13169.
  12. Cook SF, King AD, Chang Y, et al. Quantification of a biomarker of acetaminophen protein adducts in human serum by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry: clinical and animal model applications. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Mar 15;985:131-41. doi: 10.1016/j.jchromb.2015.01.028.
  13. Curry SC, Padilla-Jones A, O'Connor AD, et al. Prolonged Acetaminophen-Protein Adduct Elimination During Renal Failure, Lack of Adduct Removal by Hemodiafiltration, and Urinary Adduct Concentrations After Acetaminophen Overdose. J Med Toxicol. 2015 Jun;11(2):169-78. doi: 10.1007/s13181-014-0431-2.

Book Chapters & Review Articles

  1. Fisher ES and Curry SC. Evaluation and treatment of acetaminophen toxicity. Adv Pharmacol. 2019;85:263-272. doi: 10.1016/bs.apha.2018.12.004
  2. Curry SC and Kang AM. Hematologic Syndromes: Hemolysis, Methemoglobinemia, and Sulfhemoglobinemia. In: Brent J, Burkhart K, Dargan P, et al, eds. Critical Care Toxicology, 2nd ed. Cham, Springer International Publishing; 2017.
  3. Curry SC and Spyres MB. Cyanide: hydrogen cyanide, inorganic cyanide salts, and nitriles. In: Brent J, Burkhart K, Dargan P, et al, eds. Critical Care Toxicology, 2nd ed. Cham, Springer International Publishing; 2017.
  4. Curry SC and Spyres MB. Salicylates. In: Brent J, Burkhart K, Dargan P, et al, eds. Critical Care Toxicology, 2nd ed. Cham, Springer International Publishing; 2017.
  5. Curry SC and Spyres MB. Sodium Nitroprusside. In: Brent J, Burkhart K, Dargan P, et al, eds. Critical Care Toxicology, 2nd ed. Cham, Springer International Publishing; 2017.
  6. Raschke RA and Curry SC. Thrombolytics, heparin and derivatives, antiplaelet agents. In: Brent J, Burkhart K, Dargan P, et al, eds. Critical Care Toxicology, 2nd ed. Cham, Springer International Publishing; 2017.